These are the Billboard magazine Hot Dance Club Play number one hits of 2004.
| Issue date | Song | Artist | Reference(s) |
|---|---|---|---|
| January 3 | "Me Against the Music" | Britney Spears featuring Madonna | [1] |
| January 10 | "Are You Ready for Love" | Elton John | [2] |
| January 17 | "A Thousand Beautiful Things" | Annie Lennox | [3] |
| January 24 | "Stoned" | Dido | [4] |
| January 31 | "Wonderful" | Annie Lennox | [5] |
| February 7 | "Nothing Fails" | Madonna | [6] |
| February 14 | "Fake" | Simply Red | [7] |
| February 21 | "Give It Up" | Kevin Aviance | [8] |
| February 28 | "Slow" | Kylie Minogue | [9] |
| March 6 | "Love's Divine" | Seal | [10] |
| March 13 | "Burning" | Robbie Rivera and Axwell featuring Suzan Brittan | [11] |
| March 20 | "Face to Face" | Daft Punk | [12] |
| March 27 | "Toxic" | Britney Spears | [13] |
| April 3 | "Love Profusion" | Madonna | [14] |
| April 10 | "Not in Love" | Enrique Iglesias featuring Kelis | [15] |
| April 17 | "Save My Soul" | Kristine W | [16] |
| April 24 | "Amazing" | George Michael | [17] |
| May 1 | "Hole in the Head" | Sugababes | [18] |
| May 8 | "Never Let Me Down" | Richard "Humpty" Vission | [19] |
| May 15 | "Just a Little While" | Janet Jackson | [20] |
| May 22 | "How Did You Know" | Kurtis Mantronik presents Chamonix | [21] |
| May 29 | "Dip It Low" | Christina Milian | [22] |
| June 5 | "Naughty Girl" | Beyoncé | [23] |
| June 12 | "Strict Machine" | Goldfrapp | [24] |
| June 19 | "I'm Ready" | Cherie | [25] |
| June 26 | "Cha Cha Heels" | Rosabel with Jeanie Tracy | [26] |
| July 3 | "One with You" | Sun | [27] |
| July 10 | "Da Hype" | Junior Jack featuring Robert Smith | [28] |
| July 17 | "Back N Da Day" | Frankie Knuckles featuring Jamie Principle | [29] |
| July 24 | "All Nite (Don't Stop)" | Janet Jackson | [30] |
| July 31 | "Let the Sun Shine" | Milk & Sugar featuring Lizzy Pattinson | [31] |
| August 7 | "Push the Feeling On" | Nightcrawlers | [32] |
| August 14 | "Stolen Car (Take Me Dancing)" | Sting | [33] |
| August 21 | "That Phone Track" | DJ Dan | [34] |
| August 28 | "I Wanna Thank Ya" | Angie Stone | [35] |
| September 4 | "Push" | Ghostface featuring Missy Elliott | [36] |
| September 11 | "Flawless (Go to the City)" | George Michael | [37] |
| September 18 | "Time" | Murk | [38] |
| September 25 | "Foolish Mind Games" | Jason Walker | [39] |
| October 2 | "Stupidisco" | Junior Jack | [40] |
| October 9 | "One Rhythm" | Debi Nova | [41] |
| October 16 | "O.G. Bitch" | Esthero | [42] |
| October 23 | "How Would U Feel" | David Morales with Lea-Lorien | [43] |
| October 30 | "Devil Inside" | Utada | [44] |
| November 6 | "Dirtyfilthy" | Superchumbo featuring Celeda | [45] |
| November 13 | "Everyman...Everywoman..." | Ono | [46] |
| November 20 | "Diary" | Alicia Keys featuring Tony! Toni! Toné! | [47] |
| November 27 | "Sand in My Shoes" | Dido | [48] |
| December 4 | "(Reach Up for the) Sunrise" | Duran Duran | [49] |
| December 11 | "Which Way You're Going" | Robbie Rivera | [50] |
| December 18 | "Walk into the Sun" | Dirty Vegas | [51] |
| December 25 | "What You Waiting For?" | Gwen Stefani | [52] |
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